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BAIAP2 Mouse anti-Human, Clone: 4G7, Bioss
SDP

Catalog No. 501979797
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50-197-9797 100 μL
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Catalog No. 50-197-9797 Supplier Bioss Supplier No. BSM51410M
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Mouse Monoclonal Antibody

The protein encoded by this gene has been identified as a brain-specific angiogenesis inhibitor (BAI1)-binding protein. This adaptor protein links membrane bound G-proteins to cytoplasmic effector proteins. This protein functions as an insulin receptor tyrosine kinase substrate and suggests a role for insulin in the central nervous system. It also associates with a downstream effector of Rho small G proteins, which is associated with the formation of stress fibers and cytokinesis. This protein is involved in lamellipodia and filopodia formation in motile cells and may affect neuronal growth-cone guidance. This protein has also been identified as interacting with the dentatorubral-pallidoluysian atrophy gene, which is associated with an autosomal dominant neurodegenerative disease. Alternative splicing results in multiple transcript variants encoding distinct isoforms.

Specifications

Antigen BAIAP2
Applications Western Blot
Classification Monoclonal
Clone 4G7
Concentration 1 μg/mL
Conjugate Unconjugated
Formulation TBS with 1% BSA, 40% glycerol and 0.05% sodium azide; pH
Gene BAIAP2
Gene Accession No. Q9UQB8
Gene Alias BAI1 associated protein 2; BAI1-associated protein 2; BAIAP2; BAI-associated protein 2; BAP2; Brain-specific angiogenesis inhibitor 1-associated protein 2; Fas ligand-associated factor 3; FLAF3; insulin receptor substrate 53; insulin receptor substrate of 53 kDa; insulin receptor substrate p53; Insulin receptor substrate p53/p58; Insulin receptor substrate protein of 53 kDa; Insulin receptor tyrosine kinase 53 kDa substrate; Insulin receptor tyrosine kinase substrate protein p53; IRS-58; IRSp53; IRSp53/58; R75030
Gene Symbols BAIAP2
Host Species Mouse
Immunogen Purified His-tagged BAIAP2 protein was used to produced this monoclonal antibody.
Purification Method Protein G
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 10458
Target Species Human
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG2b
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