Invitrogen™ BAIAP2 Polyclonal Antibody

Catalog No.	Quantity
PIPA582976	100 μL

Catalog No. PIPA582976 Supplier Invitrogen™ Supplier No. PA582976

Description

Rabbit Polyclonal Antibody

Immunogen sequence: AYHSKGKELL AQKLPLWQQA CADPSKIPER AVQLMQQVAS NGATLPSALS ASKSNLVISD PIPGAKPLPV PPELAPFVGR MSAQE Highest antigen sequence indentity to the following orthologs: Rat - 92%, Mouse - 93%.

The protein encoded by this gene has been identified as a brain-specific angiogenesis inhibitor (BAI1)-binding protein. This adaptor protein links membrane bound G-proteins to cytoplasmic effector proteins. This protein functions as an insulin receptor tyrosine kinase substrate and suggests a role for insulin in the central nervous system. It also associates with a downstream effector of Rho small G proteins, which is associated with the formation of stress fibers and cytokinesis. This protein is involved in lamellipodia and filopodia formation in motile cells and may affect neuronal growth-cone guidance. This protein has also been identified as interacting with the dentatorubral-pallidoluysian atrophy gene, which is associated with an autosomal dominant neurodegenerative disease. Alternative splicing results in multiple transcript variants encoding distinct isoforms.

Specifications

• Antigen: BAIAP2
• Applications: Immunohistochemistry (Paraffin), Western Blot
• Classification: Polyclonal
• Concentration: 0.2 mg/mL
• Conjugate: Unconjugated
• Formulation: PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
• Gene: BAIAP2
• Gene Accession No.: Q6GMN2, Q8BKX1, Q9UQB8
• Gene Alias: BAI1 associated protein 2; BAI1-associated protein 2; BAIAP2; BAI-associated protein 2; BAP2; brain-specific angiogenesis inhibitor 1-associated protein 2; Fas ligand-associated factor 3; FLAF3; insulin receptor substrate 53; insulin receptor substrate of 53 kDa; insulin receptor substrate p53; insulin receptor substrate p53/p58; Insulin receptor substrate protein of 53 kDa; insulin receptor tyrosine kinase 53 kDa substrate; Insulin receptor tyrosine kinase substrate protein p53; IRS-58; IRSp53; IRSp53/58; R75030
• Gene Symbols: BAIAP2
• Host Species: Rabbit
• Immunogen: Recombinant protein corresponding to Human BAIAP2. Recombinant protein control fragment (Product #RP-93437).
• Purification Method: Antigen affinity chromatography
• Quantity: 100 μL
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 10458, 108100, 117542
• Target Species: Human, Mouse, Rat
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Product Type: Antibody
• Form: Liquid
• Isotype: IgG