Invitrogen™ BAIAP2L1 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA554365

Catalog No. PIPA554365

Description

Immunogen sequence: LLSFAQGDVI TLLIPEEKDG WLYGEHDVSK ARGWFPSSYT KLLEENETEA VTVPTPSPTP VRSISTVNLS EN Highest antigen sequence identity to the following orthologs: Mouse - 85%, Rat - 82%.

This gene encodes a member of the IMD (IRSp53/MIM homology domain) family. Members of this family can be subdivided in two groups, the IRSp53-like and MIM-like, based on the presence or absence of the SH3 (Src homology 3) domain. The protein encoded by this gene contains a conserved IMD, also known as F-actin bundling domain, at the N-terminus, and a canonical SH3 domain near the C-terminus, so it belongs to the IRSp53-like group. This protein is the substrate for insulin receptor tyrosine kinase and binds to the small GTPase Rac. It is involved in signal transduction pathways that link deformation of the plasma membrane and remodeling of the actin cytoskeleton. It also promotes actin assembly and membrane protrusions when overexpressed in mammalian cells, and is essential to the formation of a potent actin assembly complex during EHEC (Enterohemorrhagic Escherichia coli) pedestal formation.

Specifications

• Antigen: BAIAP2L1
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: BAIAP2L1
• Gene Alias: 1300006M19Rik; AI585895; BAI1 associated protein 2 like 1; BAI1-associated protein 2-like 1; BAI1-associated protein 2-like protein 1; Baiap2l1; Brain-specific angiogenesis inhibitor 1-associated protein 2-like protein 1; insulin receptor tyrosine kinase substrate; IRTKS; RGD1308452
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 304282, 55971, 66898
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
• Concentration: 0.4 mg/mL
• Formulation: PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
• Gene Accession No.: Q3KR97, Q9DBJ3, Q9UHR4
• Gene Symbols: BAIAP2L1
• Immunogen: Recombinant protein corresponding to Human BAIAP2L1. Recombinant protein control fragment (Product #RP-92593).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG