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Invitrogen™ BAIAP2L1 Polyclonal Antibody
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Catalog No. PIPA5114892
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PIPA5114892 100 μL
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Catalog No. PIPA5114892 Supplier Invitrogen™ Supplier No. PA5114892
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Description

Rabbit Polyclonal Antibody

Antibody detects endogenous levels of total BAIAP2L1.

This gene encodes a member of the IMD (IRSp53/MIM homology domain) family. Members of this family can be subdivided in two groups, the IRSp53-like and MIM-like, based on the presence or absence of the SH3 (Src homology 3) domain. The protein encoded by this gene contains a conserved IMD, also known as F-actin bundling domain, at the N-terminus, and a canonical SH3 domain near the C-terminus, so it belongs to the IRSp53-like group. This protein is the substrate for insulin receptor tyrosine kinase and binds to the small GTPase Rac. It is involved in signal transduction pathways that link deformation of the plasma membrane and remodeling of the actin cytoskeleton. It also promotes actin assembly and membrane protrusions when overexpressed in mammalian cells, and is essential to the formation of a potent actin assembly complex during EHEC (Enterohemorrhagic Escherichia coli) pedestal formation.
TRUSTED_SUSTAINABILITY

Specifications

Antigen BAIAP2L1
Applications Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide
Gene BAIAP2L1
Gene Accession No. Q3KR97, Q9DBJ3, Q9UHR4
Gene Alias 1300006M19Rik; AI585895; BAI1 associated protein 2 like 1; BAI1-associated protein 2-like 1; BAI1-associated protein 2-like protein 1; Baiap2l1; Brain-specific angiogenesis inhibitor 1-associated protein 2-like protein 1; insulin receptor tyrosine kinase substrate; IRTKS; RGD1308452
Gene Symbols BAIAP2L1
Host Species Rabbit
Immunogen A synthesized peptide derived from human BAIAP2L1(Accession Q9UHR4), corresponding to amino acid residues K113-Y163.
Purification Method Affinity Chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 304282, 55971, 66898
Target Species Human, Mouse, Rat
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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