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Invitrogen™ BAIAP2L1 Polyclonal Antibody
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Catalog No. PIPA5121180
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PIPA5121180 100 μL
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Catalog No. PIPA5121180 Supplier Invitrogen™ Supplier No. PA5121180
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Description

Rabbit Polyclonal Antibody

Positive test controls include: HepG2, HeLa, 293T, A-549, Mouse lung. The target is usually found in the following locations: Cytoplasm, cytoskeleton. Immunogen sequence: DKHCGFANHI HYYHLQSAEL LNSKLPRWQE TCVDAIKVPE KIMNMIEEIK TPASTPVSGT PQASPMIERS NVVRKDYDTL SKCSPKMPPA PSGRAYTSPL IDMFNNPATA APNSQRVNNS TGTSEDPSLQ RSVSVATGLN MMKKQKVKTI FPHTAGSNKT LLSFAQGDVI TLLIPEEKDG WLYGEHDVSK A.

This gene encodes a member of the IMD (IRSp53/MIM homology domain) family. Members of this family can be subdivided in two groups, the IRSp53-like and MIM-like, based on the presence or absence of the SH3 (Src homology 3) domain. The protein encoded by this gene contains a conserved IMD, also known as F-actin bundling domain, at the N-terminus, and a canonical SH3 domain near the C-terminus, so it belongs to the IRSp53-like group. This protein is the substrate for insulin receptor tyrosine kinase and binds to the small GTPase Rac. It is involved in signal transduction pathways that link deformation of the plasma membrane and remodeling of the actin cytoskeleton. It also promotes actin assembly and membrane protrusions when overexpressed in mammalian cells, and is essential to the formation of a potent actin assembly complex during EHEC (Enterohemorrhagic Escherichia coli) pedestal formation.
TRUSTED_SUSTAINABILITY

Specifications

Antigen BAIAP2L1
Applications ELISA, Western Blot
Classification Polyclonal
Concentration 0.96 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.01% thimerosal; pH 7.3
Gene BAIAP2L1
Gene Accession No. Q9DBJ3, Q9UHR4
Gene Alias 1300006M19Rik; AI585895; BAI1 associated protein 2 like 1; BAI1-associated protein 2-like 1; BAI1-associated protein 2-like protein 1; Baiap2l1; Brain-specific angiogenesis inhibitor 1-associated protein 2-like protein 1; insulin receptor tyrosine kinase substrate; IRTKS; RGD1308452
Gene Symbols BAIAP2L1
Host Species Rabbit
Immunogen Recombinant fusion protein containing a sequence corresponding to amino acids 198-388 of human BAIAP2L1 (NP_061330.2).
Purification Method Affinity Chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 55971, 66898
Target Species Human, Mouse
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG
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