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Epredia™ Lab Vision™ Bak Ab-2, Rabbit Polyclonal Antibody

Catalog No. RB1520R1 Shop All Epredia Products
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RB1520R1 1 mL
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Catalog No. RB1520R1 Supplier Epredia™ Supplier No. RB1520R1

Description

Obtain accurate, reproducible results in immunohistochemistry and western blotting experiments with Epredia™ Bak Ab-2, Rabbit Polyclonal Antibody.

Bak or Bcl-2-homologous antagonist is a member of the Bcl-2 family of holologous proteins which function in the regulation of apoptosis. The Bcl-2 related proteins interact with one another through the formation of homo- and heterodimers. The susceptibility of cells to apoptotic stimuli is thought to be controlled by the relative ratios of the different Bcl-2 family proteins. Bak is a 211 aa protein which has been demonstrated to accelerate the rate of apoptosis in growth factor deprived murine lymphoid, neuronal and fibroblastic cell lines. Bak has been localized by immunohistochemistry to the cytosol of cells and stains in a punctate pattern characteristic of other bcl-2 family proteins, which have been localized to intracellular organelles.

Host Species: Rabbit

Isotype: IgG

Species Reactivity: Human and Mouse. Hamster (Weakly). Others not known.

Epitope: N-terminal

Immunogen: A synthetic peptide from the N-terminus of human Bak protein

Molecular Weight: ∽24kDa

Positive Control: A431 cells, Tonsil

Cellular Localization: Cytoplasmic

Recommended for:

  • Immunohistochemistry (Formalin/paraffin)
  • Western Blotting

Note:

USA: RUO; Int'l: RUO

Specifications

Antigen Bak Ab-2
Applications Western Blot
Classification Polyclonal
Conjugate Unconjugated
Formulation Ready-to-use for IHC (UVLP)
Host Species Rabbit
Immunogen A synthetic peptide from the N-terminus of human Bak protein
Purification Method A431 cells, tonsil
Quantity 1 mL
Regulatory Status RUO
Research Discipline Apoptosis
Primary or Secondary Primary
Target Species Hamster, Human
Form Prediluted
Isotype IgG
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