Invitrogen™ BAK Monoclonal Antibody (2H9H7)

Mouse Monoclonal Antibody

Supplier:  Invitrogen™ MA548385

Catalog No. FERMA548385

Description

BAK Monoclonal Antibody for Western Blot, IHC (P), Flow, ELISA

The protein encoded by this gene belongs to the BCL2 protein family. BCL2 family members form oligomers or heterodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. This protein localizes to mitochondria, and functions to induce apoptosis. It interacts with and accelerates the opening of the mitochondrial voltage-dependent anion channel, which leads to a loss in membrane potential and the release of cytochrome c. This protein also interacts with the tumor suppressor P53 after exposure to cell stress.

Specifications

• Antigen: BAK
• Classification: Monoclonal
• Concentration: 1 mg/mL
• Formulation: PBS with 0.05% sodium azide
• Gene Accession No.: Q16611
• Gene Symbols: BAK1
• Immunogen: Purified recombinant fragment of human BAK1 (AA: 29-187) expressed in E. Coli.
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG2b

• Applications: ELISA, Flow Cytometry, Immunohistochemistry (Paraffin), Western Blot, Western Blot
• Clone: 2H9H7
• Conjugate: Unconjugated
• Gene: BAK1
• Gene Alias: Apoptosis regulator BAK; BAK; Bak1; BAK-LIKE; BCL2 antagonist/killer 1; Bcl2 homologous antagonist/killer; Bcl-2 homologous antagonist/killer; BCL2-antagonist/killer 1; BCL2L7; bcl2-L-7; BCL2-like 7 protein; BCL2-like 7protein; bcl-2-like protein 7; Bcl-2-likeous antagonist/killer; CDN1; MGC117255; MGC3887; N-Bak; N-BAK1; pro-apoptotic protein BAK
• Host Species: Mouse
• Purification Method: Protein G
• Regulatory Status: RUO
• Gene ID (Entrez): 578
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid