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Invitrogen™ BAK Polyclonal Antibody
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Catalog No. PIPA5106855
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100 μL
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PIPA5106855 100 μL
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Catalog No. PIPA5106855 Supplier Invitrogen™ Supplier No. PA5106855
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Description

Rabbit Polyclonal Antibody

Antibody detects endogenous levels of total Bak.

The protein encoded by this gene belongs to the BCL2 protein family. BCL2 family members form oligomers or heterodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. This protein localizes to mitochondria, and functions to induce apoptosis. It interacts with and accelerates the opening of the mitochondrial voltage-dependent anion channel, which leads to a loss in membrane potential and the release of cytochrome c. This protein also interacts with the tumor suppressor P53 after exposure to cell stress.
TRUSTED_SUSTAINABILITY

Specifications

Antigen BAK
Applications Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene BAK1
Gene Accession No. O08734, Q16611
Gene Alias Apoptosis regulator BAK; BAK; Bak1; BAK-LIKE; BCL2 antagonist/killer 1; Bcl2 homologous antagonist/killer; Bcl-2 homologous antagonist/killer; BCL2-antagonist/killer 1; BCL2L7; bcl2-L-7; BCL2-like 7 protein; BCL2-like 7protein; bcl-2-like protein 7; Bcl-2-likeous antagonist/killer; CDN1; MGC117255; MGC3887; N-Bak; N-BAK1; pro-apoptotic protein BAK
Gene Symbols BAK1
Host Species Rabbit
Immunogen A synthesized peptide derived from human BAK1(Accession Q16611), corresponding to amino acid residues M1-E33.
Purification Method Affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 116502, 12018, 578
Target Species Human, Mouse, Rat
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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