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Invitrogen™ BAK Recombinant Rabbit Monoclonal Antibody (7Q3T8)
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Catalog No. FEMA551515
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100 μL
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FEMA551515 100 μL
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Catalog No. FEMA551515 Supplier Invitrogen™ Supplier No. MA551515
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Description

Rabbit Recombinant Monoclonal Antibody

Immunogen sequence: RQECGEPALP SASEEQVAQD TEEVFRSYVF YRHQQEQEAE GVAAPADPEM VTLPLQPSST MGQVGRQLAI IG.

The protein encoded by this gene belongs to the BCL2 protein family. BCL2 family members form oligomers or heterodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. This protein localizes to mitochondria, and functions to induce apoptosis. It interacts with and accelerates the opening of the mitochondrial voltage-dependent anion channel, which leads to a loss in membrane potential and the release of cytochrome c. This protein also interacts with the tumor suppressor P53 after exposure to cell stress.
TRUSTED_SUSTAINABILITY

Specifications

Antigen BAK
Applications ELISA, Immunohistochemistry (Paraffin), Western Blot
Classification Recombinant Monoclonal
Clone 7Q3T8
Concentration 0.089 mg/mL
Conjugate Unconjugated
Formulation PBS with 0.05% BSA, 50% glycerol and 0.05% ProClin 300; pH 7.3
Gene BAK1
Gene Accession No. O08734, Q16611
Gene Alias Apoptosis regulator BAK; BAK; Bak1; BAK-LIKE; BCL2 antagonist/killer 1; Bcl2 homologous antagonist/killer; Bcl-2 homologous antagonist/killer; BCL2-antagonist/killer 1; BCL2L7; bcl2-L-7; BCL2-like 7 protein; BCL2-like 7protein; bcl-2-like protein 7; Bcl-2-likeous antagonist/killer; CDN1; MGC117255; MGC3887; N-Bak; N-BAK1; pro-apoptotic protein BAK
Gene Symbols BAK1
Host Species Rabbit
Immunogen Recombinant fusion protein containing a sequence corresponding to amino acids 11-82 of human Bak (NP_001179.1).
Purification Method Affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 12018, 578
Target Species Human, Mouse
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Format Liquid
Isotype IgG
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