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Tocris Bioscience™ Balicatib
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Catalog No. 558550
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558510 10 mg
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Catalog No. 558550 Supplier Tocris Bioscience™ Supplier No. 5585/50
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Description

Potent and selective cathepsin K inhibitor

Balicatib is a potent and selective cathepsin K inhibitor (IC50 values are 1.4, 56 and 480 nM for human, rat and mouse cathepsin K, respectively). Exhibits >300-fold selectivity for cathepsin K over cathepsins L, B and S. Long term supratherapeutic dosing increases tissue levels of cathepsins L and B in rats.

Specifications

Chemical Name or Material N-[1-(Cyanomethylcarbamoyl)cyclohexyl]-4-(4-propylpiperazin-1-yl)benzamide
CAS 354813-19-7
Quantity 50 mg
Target Synthetic Cathepsin Inhibitors
Molecular Formula C23H33N5O2
Formula Weight 411.54
Purity >98%
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