Invitrogen™ Band 3 Monoclonal Antibody (5G2G7)

Mouse Monoclonal Antibody

Supplier:  Invitrogen™ MA549186

Catalog No. PIMA549186

Description

Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL. Human SLC4A1 shares 75.7% and 74.5% amino acid (aa) sequence identity with and rat SLC4A1, respectively. Positive Control - WB: human K562 whole cell. IHC: human spleen tissue. Flow: HepG2 cell. Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

The Band 3 protein is the most abundant integral protein of human erythrocyte membranes and functions as the major anion transporter polypeptide of erythrocytes. Band 3 is a 90-100 kDa protein, its microheterogeneity is ascribed mainly to the structural heterogeneity of the carbohydrate moiety. The C-terminal portion of the molecule spans the membrane several times, and is responsible for anion transport. The N-terminal portion, comprising almost half of the polypeptide chain of Band 3, is located inside the red cell and interacts with cytoskeletal and cytoplasmic proteins such as ankyrin.

Specifications

• Antigen: Band 3
• Classification: Monoclonal
• Concentration: 500 μg/mL
• Formulation: PBS with 4mg trehalose and no preservative
• Gene Accession No.: P02730
• Gene Symbols: SLC4A1
• Immunogen: E.coli-derived human SLC4A1 (Position: E28-N365).
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG2b

• Applications: Flow Cytometry, Immunohistochemistry (Paraffin), Western Blot
• Clone: 5G2G7
• Conjugate: Unconjugated
• Gene: SLC4A1
• Gene Alias: AE 1; AE1; anion exchange protein 1; anion exchanger 1; anion exchanger-1; band 3 anion transport protein; BND3; CAMP; CD233; CHC; DI; Diego blood group; EMPB3; EPB3; erythrocyte membrane protein band 3; erythroid anion exchange protein; FR; Froese blood group; l11Jus51; MEB3; MGC116750; MGC116753; MGC126619; MGC126623; RTA1A; SAO; Slc4a1; solute carrier family 4 (anion exchanger), member 1; solute carrier family 4 (anion exchanger), member 1 (Diego blood group); solute carrier family 4 member 1; solute carrier family 4 member 1 (Diego blood group); solute carrier family 4, anion exchanger, member 1 (erythrocyte membrane protein band 3, Diego blood group); solute carrier family 4, anion exchanger, number 1; Solute carrier family 4, member 1, anion exchange protein 1 (kidney band 3); SPH4; SW; Swann blood group; Waldner blood group; WD; WD1; WR; Wright blood group; ZNF828
• Host Species: Mouse
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 6521
• Content And Storage: -20°C
• Form: Lyophilized