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Invitrogen™ BANF1 Polyclonal Antibody
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Catalog No. PIPA520329
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100 μg
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Catalog No. Quantity
PIPA520329 100 μg
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Catalog No. PIPA520329 Supplier Invitrogen™ Supplier No. PA520329
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Description

Rabbit Polyclonal Antibody

Despite its predicted molecular weight, BANF1 often migrates at a higher molecular weight in SDS-PAGE. A suggested positive control is mouse kidney tissue lysate. PA5-20329 can be used with blocking peptide PEP-0449.

Barrier-to-autointegration factor 1 (BANF1) is a conserved chromatin protein that non-specifically binds double-stranded DNA. BANF1 also interacts with a family of nuclear proteins that include LAP2, emerin, and MAN1. It is also a host cell component of retroviral pre-integration complexes (PICs), including that of HIV. BANF1 will bind to p55 Gag (the structural precursor of HIV-1 virions) as well as its cleaved product matrix. In addition to being a host cell component of the PIC, it is thought that BANF1 is also present at low levels in incoming virions, and thus might contribute to the assembly or activity of HIV-1 PICs through direct binding to matrix as well as DNA.
TRUSTED_SUSTAINABILITY

Specifications

Antigen BANF1
Applications Immunohistochemistry (PFA fixed), Western Blot
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 0.02% sodium azide
Gene BANF1
Gene Accession No. O54962, O75531, Q9R1T1
Gene Alias Baf; Banf1; barrier to autointegration factor 1; barrier-to-autointegration factor; Barrier-to-autointegration factor, N-terminally processed; BCRG1; Bcrp1; breakpoint cluster region protein 1; Breakpoint cluster region protein, uterine leiomyoma, 1; Breakpoint cluster region protein, uterine leiomyoma, 1; barrier to autointegration factor; D14S1460; L2bp1; L2bp1/Baf; Lap2 binding protein 1; LAP2-binding protein 1; NGPS
Gene Symbols BANF1
Host Species Rabbit
Immunogen A 19 amino acid peptide from near the amino terminus of human BANF1.
Purification Method Antigen affinity chromatography
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 114087, 23825, 8815
Target Species Human, Mouse, Rat
Content And Storage Maintain refrigerated at 2-8°C for up to 3 months. For long term storage store at -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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