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Invitrogen™ BANF1 Recombinant Rabbit Monoclonal Antibody (JG40-43)
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Catalog No. PIMA534813
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PIMA534813 100 μL
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Catalog No. PIMA534813 Supplier Invitrogen™ Supplier No. MA534813
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Description

Rabbit Recombinant Monoclonal Antibody

Positive Control: A549, MCF-7, Rat epididymis tissue, human thyroid gland tissue, human colon cancer tissue, human heart tissue, mouse testis tissue.

Barrier-to-autointegration factor 1 (BANF1) is a conserved chromatin protein that non-specifically binds double-stranded DNA. BANF1 also interacts with a family of nuclear proteins that include LAP2, emerin, and MAN1. It is also a host cell component of retroviral pre-integration complexes (PICs), including that of HIV. BANF1 will bind to p55 Gag (the structural precursor of HIV-1 virions) as well as its cleaved product matrix. In addition to being a host cell component of the PIC, it is thought that BANF1 is also present at low levels in incoming virions, and thus might contribute to the assembly or activity of HIV-1 PICs through direct binding to matrix as well as DNA.
TRUSTED_SUSTAINABILITY

Specifications

Antigen BANF1
Applications Flow Cytometry, Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
Classification Recombinant Monoclonal
Clone JG40-43
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation TBS with 0.05% BSA, 40% glycerol and 0.05% sodium azide; pH 7.4
Gene BANF1
Gene Accession No. O75531
Gene Alias Baf; Banf1; barrier to autointegration factor 1; barrier-to-autointegration factor; Barrier-to-autointegration factor, N-terminally processed; BCRG1; Bcrp1; breakpoint cluster region protein 1; Breakpoint cluster region protein, uterine leiomyoma, 1; Breakpoint cluster region protein, uterine leiomyoma, 1; barrier to autointegration factor; D14S1460; L2bp1; L2bp1/Baf; Lap2 binding protein 1; LAP2-binding protein 1; NGPS
Gene Symbols BANF1
Host Species Rabbit
Immunogen Synthetic peptide within Human BANF1 aa 1-50.
Purification Method Protein A
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 8815
Target Species Human
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG
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