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Invitrogen™ BATF Polyclonal Antibody
Rabbit Polyclonal Antibody
Supplier: Invitrogen™ PA5109444
Description
Immunogen sequence: MPHSSDSSDS SFSRSPPPGK QDSSDDVRRV QRREKNRIAA QKSRQRQTQK ADTLHLESED LEKQNAALRK EIKQLTEELK YFTSVLNSHE PLCSVLAAST PSPPEVVYSA HAFHQPHVSS PRFQP.
BATF is a nuclear basic leucine zipper protein that belongs to the AP-1/ATF superfamily of transcription factors. The leucine zipper of this protein mediates dimerization with members of the Jun family of proteins. This protein is thought to be a negative regulator of AP-1/ATF transcriptional events and blocks cellular transformation by Ras and Fos. BATF also is required for the differentiation of IL-17-producing T helper (TH17) cells, a CD4+ subset of T cells that coordinates the inflammatory response in host defense. In both T cells and B cells, BATF is required for the appropriate regulation of the class-switch recombination.
Specifications
BATF | |
Polyclonal | |
Unconjugated | |
Batf | |
activating transcription factor B; basic leucine zipper ATF-like transcription factor; basic leucine zipper transcription factor, ATF-like; basic leucine zipper transcription factor-like; basic leucine zipper transcriptional factor ATF-like; BATF; B-ATF; BATF1; B-cell activating transcription factor; B-cell-activating transcription factor; SFA2; SFA-2; SF-HT-activated gene 2 protein; si:ch211-153j24.4 | |
Rabbit | |
Affinity Chromatography | |
RUO | |
53314 | |
-20°C, Avoid Freeze/Thaw Cycles | |
Liquid |
ELISA, Western Blot | |
0.76 mg/mL | |
PBS with 50% glycerol and 0.01% thimerosal; pH 7.3 | |
O35284 | |
Batf | |
Recombinant fusion protein containing a sequence corresponding to amino acids 1-125 of human BATF (NP_006390.1). | |
100 μL | |
Primary | |
Mouse | |
Antibody | |
IgG |
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