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Invitrogen™ BATF2 Polyclonal Antibody
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Catalog No. PIPA543094
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100 μL
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PIPA543094 100 μL
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Catalog No. PIPA543094 Supplier Invitrogen™ Supplier No. PA543094
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Description

Rabbit Polyclonal Antibody

Peptide sequence: AQTAPPQPLE LEHPTRGKLG SSPDNPSSAL GLARLQSREH KPALSAATWQ Sequence homology: Dog: 85%; Human: 100%; Pig: 92%.

BATF2 (basic leucine zipper transcription factor, ATF-like 2) is a 274 amino acid protein that localizes to the nucleus and contains one bZIP domain, suggesting that it may be involved in transcriptional regulation. The gene encoding BATF2, which is expressed as multiple alternatively spliced isoforms, is located on human chromosome 11. With approximately 135 million base pairs and 1, 400 genes, chromosome 11 comprises approximately 4% of human genomic DNA and is considered a gene and disease association dense chromosome. The chromosome 11 encoded Atm gene is important for regulation of cell cycle arrest and apoptosis following double strand DNA breaks. Atm mutation leads to the disorder known as ataxia-telangiectasia. The blood disorders Sickle cell anemia and thalassemia are caused by HBB gene mutations, while Wilms' tumors, WAGR syndrome and Denys-Drash syndrome are associated with mutations of the WT1 gene. Jervell and Lange-Nielsen syndrome, Jacobsen syndrome, Niemann-Pick disease, hereditary angioedema and Smith-Lemli-Opitz syndrome are also associated with defects in chromosome 11-encoded genes.
TRUSTED_SUSTAINABILITY

Specifications

Antigen BATF2
Applications Western Blot
Classification Polyclonal
Concentration 0.5 mg/mL
Conjugate Unconjugated
Formulation PBS with 2% sucrose and 0.09% sodium azide
Gene BATF2
Gene Accession No. Q8N1L9
Gene Alias 4933430F08Rik; basic leucine zipper ATF-like transcription factor 2; basic leucine zipper transcription factor, ATF-like 2; basic leucine zipper transcriptional factor ATF-like 2; BATF2; B-ATF-2; MGC20410; RGD1311481; SARI; Suppressor of AP-1 regulated by IFN
Gene Symbols BATF2
Host Species Rabbit
Immunogen Synthetic peptide directed towards the middle region of human BATF2.
Purification Method Affinity Chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 116071
Target Species Human
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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