Invitrogen™ BATF2 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA5103647

Catalog No. PIPA5103647

Description

Antibody detects endogenous levels of total BATF2.

BATF2 (basic leucine zipper transcription factor, ATF-like 2) is a 274 amino acid protein that localizes to the nucleus and contains one bZIP domain, suggesting that it may be involved in transcriptional regulation. The gene encoding BATF2, which is expressed as multiple alternatively spliced isoforms, is located on human chromosome 11. With approximately 135 million base pairs and 1, 400 genes, chromosome 11 comprises approximately 4% of human genomic DNA and is considered a gene and disease association dense chromosome. The chromosome 11 encoded Atm gene is important for regulation of cell cycle arrest and apoptosis following double strand DNA breaks. Atm mutation leads to the disorder known as ataxia-telangiectasia. The blood disorders Sickle cell anemia and thalassemia are caused by HBB gene mutations, while Wilms' tumors, WAGR syndrome and Denys-Drash syndrome are associated with mutations of the WT1 gene. Jervell and Lange-Nielsen syndrome, Jacobsen syndrome, Niemann-Pick disease, hereditary angioedema and Smith-Lemli-Opitz syndrome are also associated with defects in chromosome 11-encoded genes.

Specifications

• Antigen: BATF2
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: BATF2
• Gene Alias: 4933430F08Rik; basic leucine zipper ATF-like transcription factor 2; basic leucine zipper transcription factor, ATF-like 2; basic leucine zipper transcriptional factor ATF-like 2; BATF2; B-ATF-2; MGC20410; RGD1311481; SARI; Suppressor of AP-1 regulated by IFN
• Host Species: Rabbit
• Purification Method: Affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 116071
• Content And Storage: -20°C
• Form: Liquid

• Applications: Western Blot
• Concentration: 1 mg/mL
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
• Gene Accession No.: Q8N1L9
• Gene Symbols: BATF2
• Immunogen: A synthesized peptide derived from human BATF2(Accession Q8N1L9), corresponding to amino acid residues S189-E239.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov