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Tocris Bioscience™ Bax channel blocker
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Catalog No. 216050 Shop All R&D Systems Products
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50 mg
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Catalog No. Quantity
21-605-0 50 mg
21-601-0R 10 mg
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Catalog No. 21-605-0 Supplier Tocris Bioscience™ Supplier No. 2160/50
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Description

Allosteric inhibitor of Bax channel activation

Bax channel blocker is a allosteric inhibitor of Bax channel activation. Binds inactive Bax at allosteric site and inhibits tBID-mediated Bax activation (IC50 = 3.3 μM). Selectively inhibits Bax-dependent apoptosis. Potent inhibitor of Bax-mediated mitochondrial cytochrome c release (IC50 = 0.52 μM).

Specifications

Quantity 50 mg
Product Type Bax channel blocker
Purity >98%
Molecular Weight (g/mol) 540.12
Inhibitors Bax channel blocker

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