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BAX Mouse anti-Human, Clone: BAX/962, Abnova™

Catalog No. 89933622 Shop All Abnova Corporation Products
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Catalog No. Quantity
89-933-622 100 μg
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Catalog No. 89-933-622 Supplier Abnova Corporation Supplier No. MAB13415
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Description

Mouse monoclonal antibody raised against full length recombinant human BAX.

The protein encoded by this gene belongs to the BCL2 protein family. BCL2 family members form hetero- or homodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. This protein forms a heterodimer with BCL2, and functions as an apoptotic activator. This protein is reported to interact with, and increase the opening of, the mitochondrial voltage-dependent anion channel (VDAC), which leads to the loss in membrane potential and the release of cytochrome c. The expression of this gene is regulated by the tumor suppressor P53 and has been shown to be involved in P53-mediated apoptosis. Multiple alternatively spliced transcript variants, which encode different isoforms, have been reported for this gene. [provided by RefSeq]

Specifications

Antigen BAX
Applications Flow Cytometry, Immunofluorescence, Immunohistochemistry (PFA fixed), Western Blot
Classification Monoclonal
Clone BAX/962
Conjugate Unconjugated
Description Mouse monoclonal antibody raised against full length recombinant human BAX.
Dilution Flow Cytometry (0.5-1 ug/106 cells in 0.1 mL) Immunofluorescence (1-2 ug/mL) Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (0.5-1 ug/mL) Western Blot (0.5-1 ug/mL) The optimal working dilution should be determ
Formulation In 10mM PBS (0.05% BSA, 0.05% sodium azide).
Gene Alias BCL2L4
Gene Symbols BAX
Host Species Mouse
Immunogen Recombinant protein corresponding to full length human BAX.
Purification Method Protein A/G purification
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 581
Test Specificity This monoclonal antibody is highly specific to Bax and shows no cross-reaction with Bcl-2 or Bcl-X protein.
Target Species Human
Content And Storage Store at 4°C.
Form Liquid
Isotype IgG1
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