Bax Mouse anti-Human, Monkey, Mouse, Rat, Alexa Fluor 594, Clone: 2D2, Novus Biologicals
Mouse Monoclonal Antibody
Manufacturer: Novus Biologicals NBP233092AF594
DescriptionBax Monoclonal antibody specifically detects Bax in Human,Monkey,Mouse,Rat samples. It is validated for ELISA.
|apoptosis regulator BAX, BCL2-associated X protein, Bcl2-L-4, BCL2L4bcl2-L-4, Bcl-2-like protein 4|
|Store at 4°C in the dark.|
|Recognizes a protein of 21kDa, identified as the Bax protein. This MAb is highly specific to Bax and shows no cross-reaction with Bcl-2 or Bcl-X protein. Bcl-2 blocks cell death following a variety of stimuli. Bax has extensive amino acid homology with Bcl-2 and it homodimerizes and forms heterodimers with Bcl-2. Overexpression of Bax accelerates apoptotic death induced by cytokine deprivation in an IL-3 dependent cell line, and Bax also counters the death repressor activity of Bcl-2.|
|Alexa Fluor™ 594|
|50 mM sodium borate with 0.05% sodium azide|
|A synthetic peptide, aa 3-16 (Cys-GSGEQPRGGGPTSS) of human bax protein.|
|Human, Monkey, Mouse, Rat|
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