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  5. Tocris Bioscience™ BAY 41-8543, >98%

Tocris Bioscience™ BAY 41-8543, >98%
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Catalog No. 570850
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Quantity:
10 mg
50 mg
This item is not returnable. View return policy
This item is not returnable. View return policy

Description

Guanylyl cyclase (sGC) stimulator

Guanylyl cyclase (sGC) stimulator. Increases activity of sGC by up to 92-fold at concentrations up to 100 μM. Induces relaxation of aorta, saphenous arteries, coronary arteries and veins in vitro. Inhibits collagen-induced platelet aggregation. Promotes lipid uptake into brown adipose tissue and increases energy expenditure in mice. Induces weight loss in obese mice. Antihypertensive.

Chemical Identifiers

CAS 256498-66-5
Molecular Formula C21H21FN8O

Specifications

Quantity 50 mg
Solubility Soluble to 10mM in DMSO with gentle warming
Formula Weight 420.44
Purity >98%
Molecular Weight (g/mol) 420.452
Chemical Name or Material 2-[1-[(2-Fluorophenyl)methyl]-1H-pyrazolo[3,4-b]pyridin-3-yl]-5-(4-morpholinyl)-4,6-pyrimidinediamin

Safety and Handling

Recommended Storage Store at -20°C
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