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Tocris Bioscience™ BAY 678

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Quantity:
5 mg
25 mg
Description
BAY 678 is a potent and selective cell-permeable human neutrophil elastase (HNE) inhibitor (IC50 = 20 nM). Exhibits around 2000-fold selectivity for NHE against a panel of 21 other serine proteases. Effective in an acute lung injury model in vivo. Orally bioavailable. Inactive S-enantiomer (Cat.No.6389) also available.
Specifications
Specifications
Chemical Name or Material | 5-[(4R)-5-Acetyl-1,2,3,4-tetrahydro-6-methyl-2-oxo-1-[3-(trifluoromethyl)phenyl]-4-pyrimidinyl]-2-pyridinecarbonitrile |
CAS | 675103-36-3 |
Assay Percent Range | >98% |
Quantity | 5 mg |
Molecular Formula | C20H15F3N4O2 |
Formula Weight | Observed MW: 400.35 |
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