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Tocris Bioscience™ BAY 826

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Quantity:
5 mg
25 mg
Description
BAY 826 is a potent Tie 2 inhibitor (IC50 = 1.3 nM for autophosphorylation of Tie2 in HUVECs), which is selective for Tie2 over other angiogenic receptor tyrosine kinases, including VEGFR, FGFR and PDGFR. BAY 826 displays in vivo efficacy in some murine glioma models.
Tie2 is also known as angiopoietin-1 receptor and TEK tyrosine kinase.
Specifications
Specifications
Chemical Name or Material | [3-Cyano-5-[[[2,4-dimethyl-5-[6-(3-pyridinyl)-1H-imidazo[1,2-b]pyrazol-1-yl]phenyl]amino]carbonyl]phenyl]pentafluorosulfur |
CAS | 1448316-08-2 |
Quantity | 5 mg |
Molecular Formula | C26H19F5N6OS |
Formula Weight | 558.53 |
Purity | 98% |
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