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  5. Tocris Bioscience™ BAY 826

Tocris Bioscience™ BAY 826
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Catalog No. 65795 Shop All Novus Biologicals Products
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65-795 5 mg
65-792-5 25 mg
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Catalog No. 65-795 Supplier Tocris Bioscience™ Supplier No. 6579/5
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Description

Potent Tie2 inhibitor

BAY 826 is a potent Tie 2 inhibitor (IC50 = 1.3 nM for autophosphorylation of Tie2 in HUVECs), which is selective for Tie2 over other angiogenic receptor tyrosine kinases, including VEGFR, FGFR and PDGFR. BAY 826 displays in vivo efficacy in some murine glioma models.

Tie2 is also known as angiopoietin-1 receptor and TEK tyrosine kinase.

Specifications

Chemical Name or Material [3-Cyano-5-[[[2,4-dimethyl-5-[6-(3-pyridinyl)-1H-imidazo[1,2-b]pyrazol-1-yl]phenyl]amino]carbonyl]phenyl]pentafluorosulfur
CAS 1448316-08-2
Quantity 5 mg
Molecular Formula C26H19F5N6OS
Formula Weight 558.53
Purity 98%
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