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Invitrogen™ BAZ2A Polyclonal Antibody
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Catalog No. PIPA5120565
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100 μL
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PIPA5120565 100 μL
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Catalog No. PIPA5120565 Supplier Invitrogen™ Supplier No. PA5120565
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Description

Rabbit Polyclonal Antibody

Positive test controls include: K-562, NIH/3T3. Immunogen sequence: QYPSANPGSN LKDPPLLSQF SGGQYPLNGI LGGSRQPSSP SHNTNLRAGS QEFWANGTQS PMGLNFDSQE LYDSFPDQNF EVMPNGPPSF FTSPQTSPML GSSIQTFAPS QEVGSGIHPD EAAEKEMTSV VAENGTGLVG SLELEEEQPE LKMCGYNGSV PSVESLHQEV SVLVPDPTVS CLDDPSHLPD QLEDTPILS.

TIP 5 is the large subunit of the nucleolar remodeling complex NoRC. NoRC causes the repression of ribosomal gene transcription. It was demonstrated that histone deacetylation is involved in this repression and that TIP5 is associated with the histone deacetylase HDAC1 and mediates the deacetylation of histones in the vicinity of the rDNA promoter. The interaction of TIP5 and HDAC1, which is necessary for transcriptional repression, is established by the C-terminal PHD finger and bromodomain.
TRUSTED_SUSTAINABILITY

Specifications

Antigen BAZ2A
Applications ELISA, Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 2.16 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.01% thimerosal; pH 7.3
Gene BAZ2A
Gene Accession No. Q9UIF9
Gene Alias AA415431; BAZ2A; bromodomain adjacent to zinc finger domain 2A; bromodomain adjacent to zinc finger domain protein 2A; bromodomain adjacent to zinc finger domain, 2A; C030005G16Rik; C78388; hWALp3; KIAA0314; mKIAA0314; TIP5; Transcription termination factor I-interacting protein 5; TTF-I interacting peptide 5; TTF-I-interacting protein 5; Walp3
Gene Symbols BAZ2A
Host Species Rabbit
Immunogen Recombinant fusion protein containing a sequence corresponding to amino acids 97-295 of human BAZ2A (NP_038477.2).
Purification Method Affinity Chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 11176
Target Species Human
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG
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