BBS10 Mouse anti-Human, Clone: 4C6A10, Proteintech

Mouse Monoclonal Antibody

Catalog Number	Mfr. No.	Quantity
50-173-7096	Proteintech Group Inc 666791IG150UL	150 μL

Description

BBS10 is a member of the Bardet-Biedl syndrome (BBS) gene family. Bardet-Biedl syndrome is an autosomal recessive disorder characterized by progressive retinal degeneration, obesity, polydactyly, renal malformation and mental retardation. The proteins encoded by BBS gene family members are structurally diverse and the similar phenotypes exhibited by mutations in BBS gene family members is likely due to their shared roles in cilia formation and function. Many BBS proteins localize to the basal bodies, ciliary axonemes, and pericentriolar regions of cells. BBS proteins may also be involved in intracellular trafficking via microtubule-related transport. The protein encoded by this gene is likely not a ciliary protein but rather has distant sequence homology to type II chaperonins. As a molecular chaperone, this protein may affect the folding or stability of other ciliary or basal body proteins. Inhibition of this protein′s expression impairs ciliogenesis in preadipocytes.

Specifications

• Antigen: BBS10
• Concentration: 0.95 mg/mL
• Classification: Monoclonal
• Form: Liquid
• Regulatory Status: RUO
• Formulation: PBS with 50% glycerol and 0.1% sodium azide; pH 7.3
• Gene Alias: Bardet Biedl syndrome 10, BBS10, C12orf58, FLJ23560
• Gene Symbols: BBS10
• Isotype: IgG2b
• Purification Method: Protein A
• Product Type: Antibody

• Clone: 4C6A10
• Applications: Immunohistochemistry (Paraffin), Western Blot
• Conjugate: Unconjugated
• Host Species: Mouse
• Target Species: Human
• Gene Accession No.: Q8TAM1
• Gene ID (Entrez): 79738
• Immunogen: BBS10 Fusion Protein Ag17960
• Primary or Secondary: Primary
• Content And Storage: -20°C
• Gene: BBS10