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Invitrogen™ BBS10 Polyclonal Antibody
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Catalog No. PIPA522028
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100 μL
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PIPA522028 100 μL
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Catalog No. PIPA522028 Supplier Invitrogen™ Supplier No. PA522028
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Description

Rabbit Polyclonal Antibody

Recommended positive controls: 293T, A431, H1299, HeLa, HepG2, Molt-4, Raji. Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

BBS10 is a member of the Bardet-Biedl syndrome (BBS) gene family. Bardet-Biedl syndrome is an autosomal recessive disorder characterized by progressive retinal degeneration, obesity, polydactyly, renal malformation and mental retardation. The proteins encoded by BBS gene family members are structurally diverse and the similar phenotypes exhibited by mutations in BBS gene family members is likely due to their shared roles in cilia formation and function. Many BBS proteins localize to the basal bodies, ciliary axonemes, and pericentriolar regions of cells. BBS proteins may also be involved in intracellular trafficking via microtubule-related transport. The protein encoded by this gene is likely not a ciliary protein but rather has distant sequence homology to type II chaperonins. As a molecular chaperone, this protein may affect the folding or stability of other ciliary or basal body proteins. Inhibition of this protein's expression impairs ciliogenesis in preadipocytes.
TRUSTED_SUSTAINABILITY

Specifications

Antigen BBS10
Applications Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation 0.1M tris glycine with 10% glycerol and 0.01% thimerosal; pH 7
Gene BBS10
Gene Accession No. Q8TAM1
Gene Alias 1300007O09Rik; AI452285; Bardet-Biedl syndrome 10; Bardet-Biedl syndrome 10 (human); Bardet-Biedl syndrome 10 protein; Bardet-Biedl syndrome 10 protein homolog; Bbs10; C12orf58; RGD1560748; si:dkey-30c15.16
Gene Symbols BBS10
Host Species Rabbit
Immunogen Recombinant protein encompassing a sequence within the center region of human BBS10. The exact sequence is proprietary.
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 79738
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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