BBS10 Rabbit anti-Human, Zebrafish, Polyclonal, Proteintech

Catalog No.	Quantity
50-172-7970	150 μL

Catalog No. 50-172-7970 Supplier Proteintech Group Inc Supplier No. 124212AP150UL

Description

Rabbit Polyclonal Antibody

BBS10 is a member of the Bardet-Biedl syndrome (BBS) gene family. Bardet-Biedl syndrome is an autosomal recessive disorder characterized by progressive retinal degeneration, obesity, polydactyly, renal malformation and mental retardation. The proteins encoded by BBS gene family members are structurally diverse and the similar phenotypes exhibited by mutations in BBS gene family members is likely due to their shared roles in cilia formation and function. Many BBS proteins localize to the basal bodies, ciliary axonemes, and pericentriolar regions of cells. BBS proteins may also be involved in intracellular trafficking via microtubule-related transport. The protein encoded by this gene is likely not a ciliary protein but rather has distant sequence homology to type II chaperonins. As a molecular chaperone, this protein may affect the folding or stability of other ciliary or basal body proteins. Inhibition of this protein′s expression impairs ciliogenesis in preadipocytes.

Specifications

• Antigen: BBS10
• Applications: Immunocytochemistry, Immunofluorescence, Western Blot
• Classification: Polyclonal
• Concentration: 0.29 mg/mL
• Conjugate: Unconjugated
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
• Gene: BBS10
• Gene Accession No.: Q8TAM1
• Gene Alias: Bardet Biedl syndrome 10, BBS10, C12orf58
• Gene Symbols: BBS10
• Host Species: Rabbit
• Immunogen: BBS10 Fusion Protein Ag3073
• Purification Method: Antigen Affinity Chromatography
• Quantity: 150 μL
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 100034535, 79738
• Target Species: Human, Zebrafish
• Content And Storage: -20°C
• Product Type: Antibody
• Form: Liquid
• Isotype: IgG