Invitrogen™ BBS2 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA596671

Catalog No. PIPA596671

Description

Immunogen sequence: MLLPVFTLKL RHKISPRMVA IGRYDGTHPC LAAATQTGKV FIHNPHTRNQ HVSASRVFQS PLESDVSLLN INQAVSCLTA GVLNPELGYD ALLVGT; Positive Samples: Mouse testis, Mouse liver, Mouse kidney, Rat liver, Rat brain, Rat lung; Cellular Location: Cell projection, Cytoplasm, centriolar satellite, centrosome, cilium membrane, cytoskeleton, microtubule organizing center.

This gene is a member of the Bardet-Biedl syndrome (BBS) gene family. Bardet-Biedl syndrome is an autosomal recessive disorder characterized by severe pigmentary retinopathy, obesity, polydactyly, renal malformation and mental retardation. The proteins encoded by BBS gene family members are structurally diverse and the similar phenotypes exhibited by mutations in BBS gene family members is likely due to their shared roles in cilia formation and function. Many BBS proteins localize to the basal bodies, ciliary axonemes, and pericentriolar regions of cells. BBS proteins may also be involved in intracellular trafficking via microtubule-related transport. The protein encoded by this gene forms a multiprotein BBSome complex with six other BBS proteins.

Specifications

• Antigen: BBS2
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: BBS2
• Gene Alias: 2410125H22Rik; AI447581; Bardet-Biedl syndrome 2; Bardet-Biedl syndrome 2 (human); Bardet-Biedl syndrome 2 homolog; Bardet-Biedl syndrome 2 protein; Bardet-Biedl syndrome 2 protein homolog; BBS; bbs2; bbs2 protein; fb80a05; MGC20703; RP74; Unknown (protein for MGC:134372); wu:fb80a05
• Host Species: Rabbit
• Purification Method: Affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 113948, 67378
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid

• Applications: ELISA, Western Blot
• Concentration: 1.58 mg/mL
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
• Gene Accession No.: Q99MH9, Q9CWF6
• Gene Symbols: BBS2
• Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-96 of human BBS2 (NP_1140913).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Mouse, Rat
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

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