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Invitrogen™ BBS9 Polyclonal Antibody
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Catalog No. PIPA5114245
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PIPA5114245 100 μL
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Catalog No. PIPA5114245 Supplier Invitrogen™ Supplier No. PA5114245
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Description

Rabbit Polyclonal Antibody

Immunogen sequence: TDSFLTVSSC QQVESYKYQV LAFATDADKR QETEQQKLGS GKRLVVDWTL For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles. Predicted homology: Cow: 100%; Dog: 100%; Guinea Pig: 93%; Horse: 100%; Human: 100%; Mouse: 86%; Pig: 100%; Rabbit: 100%; Rat: 93%.

The BBSome complex is thought to function as a coat complex required for sorting of specific membrane proteins to the primary cilia. The BBSome complex is required for ciliogenesis but is dispensable for centriolar satellite function. This ciliogenic function is mediated in part by the Rab8 GDP/GTP exchange factor, which localizes to the basal body and contacts the BBSome. Rab8(GTP) enters the primary cilium and promotes extension of the ciliary membrane. Firstly the BBSome associates with the ciliary membrane and binds to RAB3IP/Rabin8, the guanosyl exchange factor (GEF) for Rab8 and then the Rab8-GTP localizes to the cilium and promotes docking and fusion of carrier vesicles to the base of the ciliary membrane. Required for proper BBSome complex assembly and its ciliary localization.
TRUSTED_SUSTAINABILITY

Specifications

Antigen BBS9
Applications Western Blot
Classification Polyclonal
Concentration 0.5 mg/mL
Conjugate Unconjugated
Formulation PBS with 2% sucrose and 0.09% sodium azide
Gene BBS9
Gene Accession No. Q3SYG4
Gene Alias B1; Bardet-Biedl syndrome 9; Bardet-Biedl syndrome 9 (human); bardet-Biedl syndrome 9 protein; Bardet-Biedl syndrome 9 protein homolog; BBS9; C18; D1; E130103I17Rik; EST 3159894; parathyroid hormone-responsive B1 gene protein; Parathyroid hormone-responsive B1 gene protein homolog; protein PTHB1; PTHB1; PTH-responsive osteosarcoma B1 protein; RGD1308472
Gene Symbols BBS9
Host Species Rabbit
Immunogen Synthetic peptide directed towards the N-terminal region of Human BBS9 (aa 190-239).
Purification Method Affinity Chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 27241
Target Species Human
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG
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