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Tocris Bioscience™ BC-LI-0186

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Quantity:
5 mg
25 mg
Description
BC-LI-0186 is a potent and high affinity leucyl-tRNA synthase (TRS)/Ras-related GTP-binding protein D (RagD) interaction inhibitor (IC50 = 46.1 nM; Kd = 42.1 nM for binding to LRS). Inhibits mTOR complex 1 activity by blocking binding to LRS without affecting catalytic activity. Inhibits leucine-induced translocation of LRS to the lysosome.
Specifications
Specifications
Chemical Name or Material | 4-[2,5-Dihydro-2,3-dimethyl-4-(1-methylethyl)-5-oxo-1 H-pyrazol-1-yl]-N-(2-phenoxyethyl)benzenesulfonamide |
CAS | 695207-56-8 |
Quantity | 5 mg |
Target | Ras GTPase Inhibitors |
Molecular Formula | C22H27N3O4S |
Formula Weight | 1111 |
Purity | 98% |
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