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BCAR1/p130CAS Polyclonal Antibody, Bethyl Laboratories

Catalog No. 501572375
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50-157-2375 100 μL
50-157-2376 10 μL
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Catalog No. 50-157-2375 Supplier Bethyl Laboratories, Inc Supplier No. IHC00598
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Description

Rabbit Polyclonal Antibody

The recommended shelf life for this product is 1 year from date of receipt. Based on 100% sequence identity, this antibody is predicted to react with Monkey, Gorilla, Chimpanzee, Northern white-cheeked gibbon and Crab-eating macaque

The p130Cas (Cas for Crk-associated substrate) is a common cellular target of phosphorylation signal via v-Crk and v-Src oncoproteins. p130Cas has a unique structure that contains a Src homology (SH)-3 domain followed by multiple YXXP motifs and a proline-rich regionp130Cas is implicated in a variety of biological processes including cell adhesion, cell migration, growth factor stimulation, cytokine receptor engagement and bacterial infection. Physiological functions of p130Cas include cardiovascular development, actin filament assembly and Src-induced cell transformation.

Specifications

Antigen BCAR1/p130CAS
Applications Immunohistochemistry
Classification Polyclonal
Conjugate Unconjugated
Formulation TBS with 0.1% BSA and 0.09% sodium azide
Gene BCAR1
Gene Accession No. P56945, Q61140
Gene Alias Cas scaffolding protein family member 1; Crk-associated substrate p130Cas; OTTHUMP00000174941; breast cancer anti-estrogen resistance protein 1
Gene Symbols Bcar1
Host Species Rabbit
Immunogen Between 275 and 325
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 12927, 9564
Target Species Human, Mouse
Content And Storage 4° C
Product Type Antibody
Form Liquid
Isotype IgG
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