BCAR1/p130CAS Polyclonal Antibody, Bethyl Laboratories

Rabbit Polyclonal Antibody

Catalog Number	Mfr. No.	Quantity
50-156-0953	Bethyl Laboratories, Inc A301667AT	20 μL

Description

The recommended shelf life for this product is 1 year from date of receipt. Application Note: For IHC, epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.

The p130Cas (Cas for Crk-associated substrate) is a common cellular target of phosphorylation signal via v-Crk and v-Src oncoproteins. p130Cas has a unique structure that contains a Src homology (SH)-3 domain followed by multiple YXXP motifs and a proline-rich regionp130Cas is implicated in a variety of biological processes including cell adhesion, cell migration, growth factor stimulation, cytokine receptor engagement and bacterial infection. Physiological functions of p130Cas include cardiovascular development, actin filament assembly and Src-induced cell transformation.

Specifications

• Antigen: BCAR1/p130CAS
• Classification: Polyclonal
• Form: Liquid
• Regulatory Status: RUO
• Formulation: TBS with 0.1% BSA and 0.09% sodium azide
• Gene Alias: Cas scaffolding protein family member 1; Crk-associated substrate p130Cas; OTTHUMP00000174941; breast cancer anti-estrogen resistance protein 1
• Immunogen: Between 275 and 325
• Primary or Secondary: Primary
• Content And Storage: 4° C
• Gene: BCAR1

• Applications: Immunohistochemistry, Western Blot
• Conjugate: Unconjugated
• Host Species: Rabbit
• Target Species: Human, Mouse
• Gene Accession No.: P56945, Q61140
• Gene ID (Entrez): 12927, 9564
• Isotype: IgG
• Purification Method: Antigen affinity chromatography
• Product Type: Antibody