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BCAR3 Polyclonal Antibody, Bethyl Laboratories

Catalog No. 501560965
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50-156-0965 20 μL
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Catalog No. 50-156-0965 Supplier Bethyl Laboratories, Inc Supplier No. A301671AT
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Rabbit Polyclonal Antibody

The recommended shelf life for this product is 1 year from date of receipt.

Breast tumors are initially dependent on estrogens for growth and progression and can be inhibited by anti-estrogens such as tamoxifen. However, breast cancers progress to become anti-estrogen resistant. Breast cancer anti-estrogen resistance gene 3 was identified in the search for genes involved in the development of estrogen resistance. The gene encodes a component of intracellular signal transduction that causes estrogen-independent proliferation in human breast cancer cells. The protein contains a putative src homology 2 (SH2) domain, a hall mark of cellular tyrosine kinase signaling molecules, and is partly homologous to the cell division cycle protein CDC48.

Specifications

Antigen BCAR3
Applications Western Blot
Classification Polyclonal
Conjugate Unconjugated
Formulation TBS with 0.1% BSA and 0.09% sodium azide
Gene BCAR3
Gene Accession No. O75815
Gene Alias BCAR3; NSP2; SH2D3B; breast cancer anti-estrogen resistance 3; KIAA0554; OTTHUMP00000011961; breast cancer antiestrogen resistance 3; dJ1033H22.2 (breast cancer anti-estrogen resistance 3)
Gene Symbols BCAR3
Host Species Rabbit
Immunogen Between 25 and 75
Purification Method Antigen affinity chromatography
Quantity 20 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 8412
Target Species Human
Content And Storage 4° C
Product Type Antibody
Form Liquid
Isotype IgG
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