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Invitrogen™ BCAS1 Polyclonal Antibody
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Catalog No. PA14398
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100 μg
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Catalog No. Quantity
PA14398 100 μg
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Catalog No. PA14398 Supplier Invitrogen™ Supplier No. PA14398
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Description

Rabbit Polyclonal Antibody

PA1-4398 detects NABC1 in human samples. PA1-4398 has been successfully used in Western blotting procedures. By Western blot, this antibody detects a ~60 kDa protein representing NABC1 in MCF-7 cell lysates. NABC1 can form dimers, which are readily detectable in MCF-7 cells. PA1-4398 immunizing peptide corresponds to amino acid residues 532-550 of human NABC1.

BCAS1 was identified through positional cloning and was found to be overexpressed in most but not all breast cancer cells lines. Little is known about this protein; BCAS1 is cytoplasmically localized and is thought to form homodimers through coiled-coil structures. High levels of BCAS1 mRNA are seen in brain and prostate tissues, with lower amounts observed in colon, intestine and testis. Cells engineered to overexpress BCAS1 did not lose anchorage-dependent growth or increase their rate of growth, suggesting that BCAS1 is not a prototypical oncogene. The BCAS1 gene was also found to be amplified in other carcinomas such as pancreatic carcinoma, suggesting that BCAS1 may play in important role in the control of cell proliferation.
TRUSTED_SUSTAINABILITY

Specifications

Antigen BCAS1
Applications Western Blot
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 0.02% sodium azide
Gene BCAS1
Gene Accession No. O75363
Gene Alias 2210416M21Rik; 9030223A09Rik; AI841227; AIBC1; Amplified and overexpressed in breast cancer; amplified in breast cancer 1; band 83; Band83; BCAS1; breast carcinoma amplified sequence 1; breast carcinoma-amplified sequence 1; Breast carcinoma-amplified sequence 1 homolog; NABC1; Novel amplified in breast cancer 1; novel amplified in breast cancer 1 homolog; Pmes-2; Protein whose mRNA is enriched in synaptosomes 2
Gene Symbols BCAS1
Host Species Rabbit
Immunogen Synthetic peptide: D(532) T N S L Q N G D K L Q K R P E K R Q(550).
Purification Method Antigen Affinity Chromatography
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 8537
Target Species Human
Content And Storage Maintain refrigerated at 2-8°C for up to 3 months. For long term storage store at -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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