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Invitrogen™ BCAS1 Polyclonal Antibody
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Catalog No. PIPA584086
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100 μL
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PIPA584086 100 μL
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Catalog No. PIPA584086 Supplier Invitrogen™ Supplier No. PA584086
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Description

Rabbit Polyclonal Antibody

Immunogen sequence: SVKEDSVPTG AEENVVCESP VEIIKSKEVE SALQTVDLNE GDAAPEPTEA KLKREESKPR TSLMAFLRQM SVKGDGGITH SEEINGKDS Highest antigen sequence indentity to the following orthologs: Mouse - 68%, Rat - 66%.

BCAS1 was identified through positional cloning and was found to be overexpressed in most but not all breast cancer cells lines. Little is known about this protein; BCAS1 is cytoplasmically localized and is thought to form homodimers through coiled-coil structures. High levels of BCAS1 mRNA are seen in brain and prostate tissues, with lower amounts observed in colon, intestine and testis. Cells engineered to overexpress BCAS1 did not lose anchorage-dependent growth or increase their rate of growth, suggesting that BCAS1 is not a prototypical oncogene. The BCAS1 gene was also found to be amplified in other carcinomas such as pancreatic carcinoma, suggesting that BCAS1 may play in important role in the control of cell proliferation.
TRUSTED_SUSTAINABILITY

Specifications

Antigen BCAS1
Applications Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Concentration 0.3 mg/mL
Conjugate Unconjugated
Formulation PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene BCAS1
Gene Accession No. O75363
Gene Alias 2210416M21Rik; 9030223A09Rik; AI841227; AIBC1; Amplified and overexpressed in breast cancer; amplified in breast cancer 1; band 83; Band83; BCAS1; breast carcinoma amplified sequence 1; breast carcinoma-amplified sequence 1; Breast carcinoma-amplified sequence 1 homolog; NABC1; Novel amplified in breast cancer 1; novel amplified in breast cancer 1 homolog; Pmes-2; Protein whose mRNA is enriched in synaptosomes 2
Gene Symbols BCAS1
Host Species Rabbit
Immunogen Recombinant protein corresponding to Human BCAS1. Recombinant protein control fragment (Product #RP-103110).
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 8537
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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