Invitrogen™ BCAS4 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA558549

Catalog No. PIPA558549

Description

Immunogen sequence: PVALLMLLVD ADQPEPMRSG ARELALFLTP EPGAEAKEVE ETIEGMLLRL EEFCSLADLI RSDTSQILEE NIPVLKAKLT EMRGIYAKVD RL Highest antigen sequence identity to the following orthologs: Mouse - 29%, Rat - 29%.

The Breast carcinoma amplified sequence (BCAS4) gene is localized to 20q13, a region that is often amplified in breast cancers. It was isolated by the cloning of a highly overexpressed 1.3 kb transcript from the fusion of the last two exons of the BCAS3 and BCAS4 genes. This BCAS3-BCAS4 fusion transcript is only found in the MCF7 cell line, but the BCAS4 gene is also overexpressed in nine of thirteen breast cancer cell lines. The role of BCAS4 is unknown but its mRNA is highly expressed in thymus, spleen, kidney, brain, and placenta, suggesting BCAS4 plays other roles in multiple tissues.

Specifications

• Antigen: BCAS4
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: BCAS4
• Gene Alias: BCAS4; BCAS4/BCAS3 fusion; breast carcinoma amplified sequence 4; breast carcinoma amplified sequence 4/3 fusion protein; breast carcinoma-amplified sequence 4; CNOL; RP5-1071L10.2
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 55653
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Immunocytochemistry
• Concentration: 0.7 mg/mL
• Formulation: PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
• Gene Accession No.: Q8TDM0
• Gene Symbols: BCAS4
• Immunogen: Recombinant protein corresponding to Human BCAS4. Recombinant protein control fragment (Product #RP-95486).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG