Invitrogen™ BCAT1 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA5120441

Catalog No. PIPA5120441

Description

Positive test controls include: Jurkat, Raji, SH-SY5Y, Neuro-2a, Mouse brain. The target is usually found in the following locations: Cytoplasm. Immunogen sequence: EVVGTFKAKD LIVTPATILK EKPDPNNLVF GTVFTDHMLT VEWSSEFGWE KPHIKPLQNL SLHPGSSALH YAVELFEGLK AFRGVDNKIR LFQPNLNMDR MYRSAVRATL PVFDKEELLE CIQQLVKLDQ EWVPYSTSAS LYIRPTFIGT EPSLGVKKPT KALLFVLLSP V.

This gene encodes the cytosolic form of the enzyme branched-chain amino acid transaminase. This enzyme catalyzes the reversible transamination of branched-chain alpha-keto acids to branched-chain L-amino acids essential for cell growth. Two different clinical disorders have been attributed to a defect of branched-chain amino acid transamination: hypervalinemia and hyperleucine-isoleucinemia. As there is also a gene encoding a mitochondrial form of this enzyme, mutations in either gene may contribute to these disorders. Alternatively spliced transcript variants have been described.

Specifications

• Antigen: BCAT1
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: Bcat1
• Gene Alias: BCAT(c); Bcat1; BCATC; BCT1; branched chain amino acid transaminase 1; branched chain amino acid transaminase 1, cytosolic; branched chain amino-acid transaminase 1, cytosolic; branched chain aminotransferase 1, cytosolic; branched-chain-amino-acid aminotransferase, cytosolic; cytosolic branched-chain amino acid aminotransferase; Eca39; MECA39; placental protein 18; PNAS121; PP18; Protein ECA39
• Host Species: Rabbit
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 12035, 29592, 586
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid

• Applications: ELISA, Western Blot, Immunocytochemistry
• Concentration: 1.29 mg/mL
• Formulation: PBS with 50% glycerol and 0.01% thimerosal; pH 7.3
• Gene Accession No.: P24288, P54687, P54690
• Gene Symbols: Bcat1
• Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 20-190 of human BCAT1 (NP_005495.2).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG