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Invitrogen™ BCDIN3D Polyclonal Antibody
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Catalog No. PIPA5116400
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200 μL
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PIPA5116400 200 μL
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Catalog No. PIPA5116400 Supplier Invitrogen™ Supplier No. PA5116400
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Description

Rabbit Polyclonal Antibody

BCDIN3D Polyclonal Antibody for Western Blot

O-methyltransferase that specifically monomethylates 5'- monophosphate of cytoplasmic histidyl tRNA (tRNA(His)), acting as a capping enzyme by protecting tRNA(His) from cleavage by DICER1. Also able, with less efficiently, to methylate the 5' monophosphate of a subset of pre- miRNAs, acting as a negative regulator of miRNA processing. The 5' monophosphate of pre-miRNAs is recognized by DICER1 and is required for pre-miRNAs processing: methylation at this position reduces the processing of pre-miRNAs by DICER1. Was also reported to mediate dimethylation of pre-miR-145; however dimethylation cannot be reproduced by another group which observes a monomethylation of pre-miR-145.
TRUSTED_SUSTAINABILITY

Specifications

Antigen BCDIN3D
Applications Western Blot
Classification Polyclonal
Concentration 0.5 mg/mL
Conjugate Unconjugated
Formulation PBS with 0.09% sodium azide; pH 7.4
Gene BCDIN3D
Gene Accession No. Q7Z5W3
Gene Alias BCDIN3 domain containing RNA methyltransfease; BCDIN3 domain containing RNA methyltransferase; BCDIN3 domain-containing protein; BCDIN3D; pre-miRNA 5'-monophosphate methyltransferase; probable methyltransferase BCDIN3D; RNA 5'-monophosphate methyltransferase
Gene Symbols BCDIN3D
Host Species Rabbit
Immunogen KLH conjugated synthetic peptide between 243-276 amino acids from human BCDIN3D.
Purification Method Antigen affinity chromatography, Protein A
Quantity 200 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 144233
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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