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Invitrogen™ Bcl-10 Polyclonal Antibody
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Catalog No. PA14129
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100 μg
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Catalog No. Quantity
PA14129 100 μg
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Catalog No. PA14129 Supplier Invitrogen™ Supplier No. PA14129
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Description

Rabbit Polyclonal Antibody

PA1-4129 detects Bcl10 in human samples. PA1-4129 has been successfully used in Western blot procedures. By Western blot this antibody detects a ~26 kDa protein representing Bcl10 in transfected 293 cells. The PA1-4129 immunogen is a synthetic peptide corresponding to residues E(220) M F L P L R S R T V S R Q(233) C of Bcl10.

BCL-10 is an N-terminal CARD (Caspase Recruitment Domain) containing protein that is involved in the adaptive immune response. It promotes apoptosis, pro-caspase-9 maturation, and activation of NF-kappa-B via NIK and IKK. BCL-10 is also an adapter protein between upstream TNFR1-TRADD-RIP complex and the downstream NIK-IKK-IKAP complex. It is a substrate for MALT1. Mutations in the gene can lead to Immmunodeficiency 37 or Lymphoma, mucosa-associated lymphoid type.
TRUSTED_SUSTAINABILITY

Specifications

Antigen Bcl-10
Applications Western Blot
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 0.02% sodium azide
Gene BCL10
Gene Accession No. O95999
Gene Alias AI132454; B cell CLL/lymphoma 10; B cell leukemia/lymphoma 10; B-cell CLL/lymphoma 10; B-cell leukemia/lymphoma 10; B-cell lymphoma/leukemia 10; BCL10; Bcl-10; BCL10 immune signaling adaptor; C81403; CARD containing molecule enhancing NF-kB; CARD-containing apoptotic signaling protein; CARD-containing molecule enhancing NF-kappa-B; CARD-containing proapoptotic protein; CARD-like apoptotic protein; CARMEN; caspase-recruiting domain-containing protein; cCARMEN; cE10; c-E10; CED-3/ICH-1 prodomain homologous E10-like regulator; cellular homolog of vCARMEN; Cellular-E10; CIPER; Clap; hCLAP; IMD37; Mamm; mammalian CARD-containing adapter molecule E10; mCIPER; mCLAP; mE10; OTTHUMP00000011647; OTTHUMP00000036080; RCD; RP11-234D19.2; R-RCD1
Gene Symbols BCL10
Host Species Rabbit
Immunogen Synthetic peptide corresponding to residues E(220) M F L P L R S R T V S R Q(233) C of Bcl10.
Purification Method Antigen affinity chromatography
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 8915
Target Species Human
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG
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