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Invitrogen™ Bcl-3 Monoclonal Antibody (Ham150-3.5)
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Catalog No. MA1950
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Quantity:
100 μg
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Catalog No. Quantity
MA1-950 100 μg
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Catalog No. MA1-950 Supplier Invitrogen™ Supplier No. MA1950
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Description

Armenian Hamster Monoclonal Antibody

MA1-950 detects human and mouse Bcl-3 from transfected cells and shows no cross-reactivity to other Bcl isoforms. MA1-950 has been successfully used in Western blot and FACS procedures. By Western blot, this antibody detects an ~47 kDa protein representing Bcl-3 from C57BI/6 human T cells and Bcl-3 transgenic ms T cells. MA1-950 immunogen is full length Bcl-3 protein from mouse.

B cell Lymphoma 3 is a member of the IkB subfamily of inhibitors. This subfamily is part of the NF-kB transcription factor protein family and it is suggested that a balance in the concentration of various NF-kB family members regulates apoptosis and survival of activated T cells. Bcl-3 has been shown to have versatile functions such as cytoplasmic activation of p50 homodimers, translocation to the nucleus, and modulation of the transcriptional machinery in the nucleus. Bcl-3 activity often relies on several nuclear interacting proteins such as Tip60, Jab1, Bard1, and Pirin.
TRUSTED_SUSTAINABILITY

Specifications

Antigen Bcl-3
Applications ELISA, Flow Cytometry, Western Blot
Classification Monoclonal
Clone Ham150-3.5
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 1mg/mL BSA and 0.05% sodium azide
Gene Bcl3
Gene Accession No. P20749, Q9Z2F6
Gene Alias AI528691; B cell leukemia/lymphoma 3; B-cell CLL/lymphoma 3; B-cell leukemia/lymphoma 3; B-cell lymphoma 3 protein; B-cell lymphoma 3 protein homolog; B-cell lymphoma 3-encoded protein; BCL3; BCL-3; Bcl-3 protein; BCL4; chronic lymphatic leukemia protein; D19S37; Proto-oncogene BCL3
Gene Symbols Bcl3
Host Species Armenian Hamster
Immunogen Full length mouse Bcl-3 protein.
Purification Method Protein G
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 12051, 602
Target Species Human, Mouse
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Reproductive Harm - www.P65Warnings.ca.gov
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