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Invitrogen™ Bcl-B Monoclonal Antibody (8A2F9)
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Catalog No. PIMA531647
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100 μL
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Catalog No. Quantity
PIMA531647 100 μL
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Catalog No. PIMA531647 Supplier Invitrogen™ Supplier No. MA531647
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Description

Mouse Monoclonal Antibody

MA5-31647 has been tested in indirect ELISA.

The protein encoded by this gene belongs to the BCL-2 protein family. BCL-2 family members form hetero- or homodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. The protein encoded by this gene contains conserved BH4, BH1 and BH2 domains. This protein can interact with other members of BCL-2 protein family including BCL2, BCL2L1/BCL-X(L), and BAX. Overexpression of this gene has been shown to suppress cell apoptosis possibly through the prevention of cytochrome C release from the mitochondria, and thus activating caspase-3 activation. The mouse counterpart of this protein is found to interact with Apaf1 and forms a protein complex with Caspase 9, which suggests the involvement of this protein in APAF1 and CASPASE 9 related apoptotic pathway.
TRUSTED_SUSTAINABILITY

Specifications

Antigen Bcl-B
Applications ELISA, Flow Cytometry, Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
Classification Monoclonal
Clone 8A2F9
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 0.05% sodium azide
Gene BCL2L10
Gene Accession No. Q9HD36
Gene Alias AA420380; anti-apoptotic protein Boo; Anti-apoptotic protein NrH; apoptosis regulator Bcl-B; AU023065; Bcl-2 homolog Diva; BCL2 like 10; BCL2L10; bcl2-L-10; Bcl2-like 10; BCL2-like 10 (apoptosis facilitator); bcl-2-like protein 10; BCLB; BCL-B; Boo; C85687; death inducer binding to vBcl-2 and Apaf-1; Diva
Gene Symbols BCL2L10
Host Species Mouse
Immunogen Purified recombinant fragment of human BCL2L10 (AA: 31-186) expressed in E. coli.
Purification Method Protein G
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 10017
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG1
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