Invitrogen™ Bcl-W Monoclonal Antibody (F.584.7)

Catalog No.	Quantity
PIMA515076	100 μL

Catalog No. PIMA515076 Supplier Invitrogen™ Supplier No. MA515076

Description

Rabbit Monoclonal Antibody

It is not recommended to aliquot this antibody.

Using a PCR-based strategy, an additional protein with life-promoting activity, designated Bcl-w, has been identified. The protein is highly conserved between mouse and human and is encoded by a gene located near the TCRalpha gene on chromosome 14. Bcl-w is expressed in myeloid cell lines but not in T and B lymphocytes, and can be found in a wide range of tissues. An alternative splicing event in exon 4 results in two transcripts. The first, Bcl-w, encodes a protein of 193 amino acids, and the second, Bcl-w/rox, encodes a protein 333 amino acids in length. The 'rox' portion of Bcl-w/rox shows a striking 66% amino acid sequence identity with the Drosophila rox2 protein; however, the Bcl-w/rox transcript may be expressed at very low levels.

Specifications

• Antigen: Bcl-W
• Applications: Western Blot
• Classification: Monoclonal
• Clone: F.584.7
• Concentration: 107 μg/mL
• Conjugate: Unconjugated
• Formulation: 0.01M HEPES with 0.15M NaCl, 100μg/mL BSA, 50% glycerol and <0.02% sodium azide; pH 7.5
• Gene: BCL2L2
• Gene Accession No.: P70345, Q92843
• Gene Alias: Apoptosis regulator Bcl-W; AW048834; BCL2 like 2; BCL2L2; BCL2-L-2; BCL2-like 2; BCL2-like 2 protein; Bcl-2-like protein 2; Bcl2-like protein 2; BCLW; BCL-W; BCL-WEL; BCL-WS; c98; Gtrgal2; Gtrosa41; Kiaa0271; PPP1R51; protein phosphatase 1, regulatory subunit 51
• Gene Symbols: BCL2L2
• Host Species: Rabbit
• Immunogen: Synthetic peptide corresponding to residues surrounding alanine 39 of Bcl-w.
• Purification Method: Affinity chromatography
• Quantity: 100 μL
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 12050, 599, 60434
• Target Species: Human, Mouse, Rat
• Content And Storage: -20°C
• Product Type: Antibody
• Form: Liquid
• Isotype: IgG