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bcl-x Antibody (BX006), HRP, Novus Biologicals™
SDP

Catalog No. NBP233164H Shop All R&D Systems Products
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NBP233164H 0.1 mL
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Catalog No. NBP233164H Supplier Novus Biologicals Supplier No. NBP233164H
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Description

Mouse Monoclonal Antibody

Bcl-xL Monoclonal specifically detects Bcl-xL in Human, Mouse, Rat, Porcine samples. It is validated for Western Blot, Immunohistochemistry, Immunohistochemistry-Paraffin.

Specifications

Antigen Bcl-xL
Applications Western Blot, ELISA, Immunohistochemistry, Immunohistochemistry (Paraffin), Immunohistochemistry (Frozen), Immunoprecipitation
Classification Monoclonal
Clone BX006
Conjugate HRP
Dilution Western Blot 1:100-1:2000, ELISA 1-5 μg/mL for coating, Immunohistochemistry, Immunohistochemistry-Paraffin 1:10-1:500, Immunohistochemistry-Frozen 1:10-1:500
Gene Alias Apoptosis regulator Bcl-X, bcl2-L-1, BCL2-like 1, bcl-2-like protein 1, BCLXBCL2LBcl-X, bcl-xL, BCLXL, BCL-XL/S, bcl-xS, BCLXS, DKFZp781P2092
Gene Symbols BCL2L1
Host Species Mouse
Immunogen A synthetic peptide, aa 3-14 (Cys-QSNRELVVDFLS) of human Bcl-xL protein. (Uniprot: Q07817)
Molecular Weight of Antigen 27 kDa
Purification Method Protein A or G purified
Quantity 0.1 mL
Regulatory Status RUO
Research Discipline Apoptosis, Cancer, Phospho Specific, Tumor Suppressors
Primary or Secondary Primary
Gene ID (Entrez) 598
Test Specificity Recognizes a protein of 27kDa, identified as the Bcl-X protein. This monoclonal antibody shows no cross-reaction with Bcl-2 or Bax protein. Bcl-X has two isoforms, Bcl-XL (long), a 241 amino acid protein which suppresses cell death. And Bcl-XS (short), a 178 amino acid protein lacking a 63 amino acid domain which functions as a dominant inhibitor of Bcl-2. This monoclonal antibody reacts with both Bcl-XS and Bcl-XL proteins.
Target Species Human, Mouse, Rat, Pig
Content And Storage Store at 4C in the dark.
Form Purified
Isotype IgG2a κ
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For Research Use Only

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