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Bcl-XL Mouse anti-Human, Clone: OTI4A9, liquid, TrueMAB™
SDP

Mouse Monoclonal Antibody

Supplier:  OriGene TA500097S

Encompass_Preferred

Catalog No. 50-167-1397


May include imposed supplier surcharges.
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Description

Description

BCL-XL is a part of the BCL-2 protein family. BCL-2 family members form hetero- or homodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. BCL-XL is located at the outer mitochondrial membrane, and have been shown to regulate outer mitochondrial membrane channel (VDAC) opening. VDAC regulates mitochondrial membrane potential and controls the production of reactive oxygen species and release of cytochrome C by mitochondria, both of which are the potent inducers of cell apoptosis. Two alternatively spliced transcript variants, which encode distinct isoforms, have been reported. The longer isoform acts as an apoptotic inhibitor and the shorter form acts as an apoptotic activator.
Specifications

Specifications

Bcl-XL
Monoclonal
0.25 mg/mL
PBS with 1% BSA, 50% glycerol and 0.02% sodium azide
Q07817
BCL2L1
Recombit fragment expressed in E.coli corresponding to amino acids 1-212 of human Bcl-XL
30 μL
Primary
Human
Antibody
IgG2a
Immunocytochemistry, Immunofluorescence, Western Blot
OTI4A9
Unconjugated
BCL2L1
BCL-XL/S, BCL2L, BCLX, Bcl-X, PPP1R52
Mouse
Protein A
RUO
598
-20° C, Avoid Freeze/Thaw Cycles
Liquid
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