BCL10 Monoclonal Antibody (OTI2G9), TrueMAB™, OriGene

Mouse Monoclonal Antibody

Supplier:  OriGene TA800455

Catalog No. 50-167-8337

Description

BCL-10 is an N-terminal CARD (Caspase Recruitment Domain) containing protein that is involved in the adaptive immune response. It promotes apoptosis, pro-caspase-9 maturation, and activation of NF-kappa-B via NIK and IKK. BCL-10 is also an adapter protein between upstream TNFR1-TRADD-RIP complex and the downstream NIK-IKK-IKAP complex. It is a substrate for MALT1. Mutations in the gene can lead to Immmunodeficiency 37 or Lymphoma, mucosa-associated lymphoid type.

Specifications

• Antigen: BCL10
• Classification: Monoclonal
• Concentration: 1 mg/mL
• Formulation: PBS with 1% BSA, 50% glycerol and 0.02% sodium azide
• Gene Accession No.: O95999
• Gene Symbols: BCL10
• Immunogen: Full length human recombit protein of human BCL10 produced in HEK293T cell.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG1

• Applications: Western Blot
• Clone: OTI2G9
• Conjugate: Unconjugated
• Gene: BCL10
• Gene Alias: CARMEN, CIPER, CLAP, IMD37, c-E10, mE10
• Host Species: Mouse
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 8915
• Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
• Form: Liquid