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BCL10 Mouse anti-Human, Clone: 2E8G5, Proteintech
SDP

Catalog No. 501736975 Shop All Proteintech Group Inc Products
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150 μL
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50-173-6975 150 μL
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Catalog No. 50-173-6975 Supplier Proteintech Group Inc Supplier No. 665561IG150UL
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Description

Mouse Monoclonal Antibody

BCL-10 is an N-terminal CARD (Caspase Recruitment Domain) containing protein that is involved in the adaptive immune response. It promotes apoptosis, pro-caspase-9 maturation, and activation of NF-kappa-B via NIK and IKK. BCL-10 is also an adapter protein between upstream TNFR1-TRADD-RIP complex and the downstream NIK-IKK-IKAP complex. It is a substrate for MALT1. Mutations in the gene can lead to Immmunodeficiency 37 or Lymphoma, mucosa-associated lymphoid type.

Specifications

Antigen BCL10
Applications Immunohistochemistry (Paraffin), Western Blot
Classification Monoclonal
Clone 2E8G5
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.1% sodium azide; pH 7.3
Gene BCL10
Gene Accession No. O95999
Gene Alias B cell CLL/lymphoma 10, B cell lymphoma/leukemia 10, BCL10, c E10, CARD like apoptotic protein, CARMEN, cCARMEN, Cellular E10, Cellular homolog of vCARMEN, CIPER, CLAP, hCLAP, mE10
Gene Symbols BCL10
Host Species Mouse
Immunogen BCL10 Fusion Protein Ag12162
Purification Method Protein G
Quantity 150 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 8915
Target Species Human
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG1
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