BCL10 Mouse anti-Human, Clone: OTI4H9, lyophilized, TrueMAB™

Mouse Monoclonal Antibody

Supplier:  OriGene CF800445

Catalog No. 50-166-5095

Description

Reconstitute with PBS (pH 7.3) and recommend to perform another round of desalting process using Product No. 7KMWCO

BCL-10 is an N-terminal CARD (Caspase Recruitment Domain) containing protein that is involved in the adaptive immune response. It promotes apoptosis, pro-caspase-9 maturation, and activation of NF-kappa-B via NIK and IKK. BCL-10 is also an adapter protein between upstream TNFR1-TRADD-RIP complex and the downstream NIK-IKK-IKAP complex. It is a substrate for MALT1. Mutations in the gene can lead to Immmunodeficiency 37 or Lymphoma, mucosa-associated lymphoid type.

Specifications

• Antigen: BCL10
• Classification: Monoclonal
• Conjugate: Unconjugated
• Gene: BCL10
• Gene Alias: CARMEN, CIPER, CLAP, IMD37, c-E10, mE10
• Host Species: Mouse
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 8915
• Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
• Form: Lyophilized

• Applications: Immunohistochemistry (Paraffin), Western Blot
• Clone: OTI4H9
• Formulation: PBS with 8% trehalose and no preservative; pH 7.3
• Gene Accession No.: O95999
• Gene Symbols: BCL10
• Immunogen: Full length human recombit protein of human BCL10 produced in HEK293T cell.
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG1