BCL11A Monoclonal Antibody (BCL11A/123), Active Motif™

Mouse Monoclonal Antibody

Supplier:  Active Motif 61232

Catalog No. 50-199-3253

Description

This gene encodes a C2H2 type zinc-finger protein by its similarity to the mouse Bcl11a/Evi9 protein. The corresponding mouse gene is a common site of retroviral integration in myeloid leukemia, and may function as a leukemia disease gene, in part, through its interaction with BCL6. During hematopoietic cell differentiation, this gene is down-regulated. It is possibly involved in lymphoma pathogenesis since translocations associated with B-cell malignancies also deregulates its expression. Multiple transcript variants encoding several different isoforms have been found for this gene.

Specifications

• Antigen: BCL11A
• Classification: Monoclonal
• Concentration: 1 mg/mL
• Formulation: PBS with 30% glycerol and 0.035% sodium azide; pH 7.5
• Gene Accession No.: Q9H165
• Gene Symbols: BCL11A
• Immunogen: This BCL11A antibody was raised against a recombinant protein corresponding to amino acids 637-835 of BCL11A-XL (B-cell lymphoma/leukemia 11A extra long form).
• Quantity: 10 μg
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG1

• Applications: Western Blot
• Clone: BCL11A/123
• Conjugate: Unconjugated
• Gene: BCL11A
• Gene Alias: 2810047E18Rik; B cell CLL/lymphoma 11A (zinc finger protein); B-cell CLL/lymphoma 11A; B-cell CLL/lymphoma 11A (zinc finger protein); B-cell CLL/lymphoma 11A (zinc finger protein) isoform 2; B-cell lymphoma/leukemia 11A; Bcl11a; BCL-11A; BCL11A B-cell CLL/lymphoma 11A (zinc finger protein) isoform 1; BCL11A, BAF complex component; BCL11A-L; BCL11a-M; BCL11A-S; BCL11A-XL; BOS_11500; C2H2-type zinc finger protein; COUP-TF interacting protein 1; COUP-TF-interacting protein 1; Ctip1; D930021L15Rik; ecotropic viral integration site 9 homolog; Ecotropic viral integration site 9 protein; Ecotropic viral integration site 9 protein homolog; EVI9; EVI-9; Evi9a; Evi9b; Evi9c; FLJ10173; FLJ34997; HBFQTL5; KIAA1809; mKIAA1809; myeloid leukemia; Zinc finger protein 856; ZNF856
• Host Species: Mouse
• Purification Method: Protein G
• Regulatory Status: RUO
• Gene ID (Entrez): 53335
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid