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Invitrogen™ BCL11A Polyclonal Antibody
Rabbit Polyclonal Antibody
Supplier: Invitrogen™ PA5114898
Description
Antibody detects endogenous levels of total BCL11A.
This gene encodes a C2H2 type zinc-finger protein by its similarity to the mouse Bcl11a/Evi9 protein. The corresponding mouse gene is a common site of retroviral integration in myeloid leukemia, and may function as a leukemia disease gene, in part, through its interaction with BCL6. During hematopoietic cell differentiation, this gene is down-regulated. It is possibly involved in lymphoma pathogenesis since translocations associated with B-cell malignancies also deregulates its expression. Multiple transcript variants encoding several different isoforms have been found for this gene.
Specifications
BCL11A | |
Polyclonal | |
Unconjugated | |
BCL11A | |
2810047E18Rik; B cell CLL/lymphoma 11A; B cell CLL/lymphoma 11A (zinc finger protein); BAF chromatin remodeling complex subunit BCL11A; B-cell CLL/lymphoma 11A; B-cell CLL/lymphoma 11A (zinc finger protein); B-cell CLL/lymphoma 11A (zinc finger protein) isoform 2; B-cell lymphoma/leukemia 11A; BCL11A; BCL-11A; BCL11A B-cell CLL/lymphoma 11A (zinc finger protein) isoform 1; BCL11A, BAF complex component; BCL11A-L; BCL11a-M; BCL11A-S; BCL11A-XL; C2H2-type zinc finger protein; COUP-TF interacting protein 1; COUP-TF-interacting protein 1; CTIP1; D930021L15Rik; ecotropic viral integration site 9 homolog; ecotropic viral integration site 9 protein; Ecotropic viral integration site 9 protein homolog; Evi9; EVI-9; Evi9a; Evi9b; Evi9c; FLJ10173; FLJ34997; HBFQTL5; Kiaa1809; mKIAA1809; myeloid leukemia; zinc finger protein 856; ZNF856 | |
Rabbit | |
Affinity Chromatography | |
RUO | |
14025, 305589, 53335 | |
-20°C | |
Liquid |
Immunohistochemistry (Paraffin), Western Blot | |
1 mg/mL | |
PBS with 50% glycerol and 0.02% sodium azide | |
Q9H165, Q9QYE3 | |
BCL11A | |
A synthesized peptide derived from human BCL11A(Accession Q9H165), corresponding to amino acid residues T180-I230. | |
100 μL | |
Primary | |
Human, Mouse, Rat | |
Antibody | |
IgG |
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