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Invitrogen™ BCL11A Recombinant Rabbit Monoclonal Antibody (JB35-68)
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Catalog No. PIMA534678
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PIMA534678 100 μL
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Catalog No. PIMA534678 Supplier Invitrogen™ Supplier No. MA534678
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Description

Rabbit Recombinant Monoclonal Antibody

Positive Control: Daudi, U937, human tonsil tissue, mouse cerebellum tissue, Jurkat.

This gene encodes a C2H2 type zinc-finger protein by its similarity to the mouse Bcl11a/Evi9 protein. The corresponding mouse gene is a common site of retroviral integration in myeloid leukemia, and may function as a leukemia disease gene, in part, through its interaction with BCL6. During hematopoietic cell differentiation, this gene is down-regulated. It is possibly involved in lymphoma pathogenesis since translocations associated with B-cell malignancies also deregulates its expression. Multiple transcript variants encoding several different isoforms have been found for this gene.
TRUSTED_SUSTAINABILITY

Specifications

Antigen BCL11A
Applications Flow Cytometry, Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
Classification Recombinant Monoclonal
Clone JB35-68
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation TBS with 0.05% BSA, 40% glycerol and 0.05% sodium azide; pH 7.4
Gene BCL11A
Gene Accession No. Q9H165
Gene Alias 2810047E18Rik; B cell CLL/lymphoma 11A; B cell CLL/lymphoma 11A (zinc finger protein); BAF chromatin remodeling complex subunit BCL11A; B-cell CLL/lymphoma 11A; B-cell CLL/lymphoma 11A (zinc finger protein); B-cell CLL/lymphoma 11A (zinc finger protein) isoform 2; B-cell lymphoma/leukemia 11A; BCL11A; BCL-11A; BCL11A B-cell CLL/lymphoma 11A (zinc finger protein) isoform 1; BCL11A, BAF complex component; BCL11A-L; BCL11a-M; BCL11A-S; BCL11A-XL; C2H2-type zinc finger protein; COUP-TF interacting protein 1; COUP-TF-interacting protein 1; CTIP1; D930021L15Rik; ecotropic viral integration site 9 homolog; ecotropic viral integration site 9 protein; Ecotropic viral integration site 9 protein homolog; Evi9; EVI-9; Evi9a; Evi9b; Evi9c; FLJ10173; FLJ34997; HBFQTL5; Kiaa1809; mKIAA1809; myeloid leukemia; zinc finger protein 856; ZNF856
Gene Symbols BCL11A
Host Species Rabbit
Immunogen Recombinant protein within Human Ctip1 aa 381-609.
Purification Method Protein A
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 53335
Target Species Human
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG
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