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Invitrogen™ BCL2A1 Polyclonal Antibody
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Catalog No. PIPA5143077
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100 μg
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PIPA5143077 100 μg
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Catalog No. PIPA5143077 Supplier Invitrogen™ Supplier No. PA5143077
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Description

Goat Polyclonal Antibody

Additional Information: This antibody may cross-react with the almost identical proteins A1b (GeneID 12045) and A1d (GeneID 12047). This antibody is tested in Peptide ELISA: antibody detection limit dilution 1:128,000.

Bcl-2 related Protein A1 is a member of the BCL-2 protein family. The proteins of this family form hetero- or homodimers and act as anti- and pro-apoptotic regulators that are involved in a wide variety of cellular activities such as embryonic development, homeostasis and tumorigenesis. The protein encoded by this gene is able to reduce the release of pro-apoptotic cytochrome c from mitochondria and block caspase activation. This gene is a direct transcription target of NF-kappa B in response to inflammatory mediators, and has been shown to be up-regulated by different extracellular signals, such as granulocyte-macrophage colony-stimulating factor (GM-CSF), CD40, phorbol ester and inflammatory cytokine TNF and IL-1, which suggests a cytoprotective function that is essential for lymphocyte activation as well as cell survival.
TRUSTED_SUSTAINABILITY

Specifications

Antigen BCL2A1
Applications Western Blot
Classification Polyclonal
Concentration 0.5 mg/mL
Conjugate Unconjugated
Formulation TBS with 0.5% BSA and 0.02% sodium azide; pH 7.3
Gene BCL2A1
Gene Accession No. 0
Gene Alias A1; A1-A; ACC1; ACC-1; ACC2; ACC-2; B cell leukemia/lymphoma 2 related protein A1a; BB218357; B-cell leukemia/lymphoma 2 related protein A1; B-cell leukemia/lymphoma 2 related protein A1a; B-cell leukemia/lymphoma 2 related protein A1d; BCL2 related protein A1; Bcl2a1; Bcl2a1a; Bcl2a1d; BCL2L5; bcl2-L-5; Bcl-2-like protein 5; bcl-2-related protein A1; BCL2-related protein A1; BCL2-related protein A1d; Bfl1; Bfl-1; GRS; GRS protein; HBPA1; hematopoietic BCL2-related protein A1; hemopoietic-specific early response protein; Protein BFL-1; Protein GRS
Gene Symbols BCL2A1
Host Species Goat
Immunogen Peptide with sequence C-QKEVEKNLKPYLDD.
Purification Method Ammonium Sulfate Precipitation
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 170929
Target Species Rat
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG
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